APC2 Antibody (YA3578)
(Synonyms: APCL)APC2 Antibody (YA3578) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to APC2.
-
Host:
Mouse
-
Isotype:
IgG1
-
Application:
IHC-P, ICC/IF, FC, ELISA
-
Reactivity :
Human
-
Formulation:
Supplied in PBS with 0.05% sodium azide
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
|
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
|
|---|---|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:200-1:1000 | 1:200-1:400 | 1:10000 |
Product Details
APC2 Antibody (YA3578) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to APC2.
-
Host Mouse
-
Clonality Monoclonal
-
Species ReactivityHuman
-
Observed Molecular WeightObserved band size: 97 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 244 kDa
Purified recombinant fragment of human APC2 (AA: 2041-2181) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in PBS with 0.05% sodium azide
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
APC2 is a Stabilizes microtubules and may regulate actin fiber dynamics through the activation of Rho family GTPases. May also function in Wnt signaling by promoting the rapid degradation of CTNNB1[1][2][3][4].
-
Subcellular Localization
Cytoplasm, cytoskeleton; Golgi apparatus; Cytoplasm; Cytoplasm, perinuclear region
-
Expression
Tissue_specificity:Widely expressed (at protein level) . Specifically expressed in the CNS -
Isoforms & Post-Translational Modification
O95996 has 3 isomers: O95996-1: 243949 Da (predicted); O95996-2: 213799 Da (predicted); O95996-3: 243821 Da (predicted).
-
Subunit
Interacts with APC (PubMed:11691822). Interacts with CTNNB1 (PubMed:9823329). Interacts with MAPRE1 and MAPRE3 (PubMed:10644998). Interacts with TP53BP (PubMed:10646860). Interacts possibly with AXIN2 (PubMed:10021369)
-
SwissProt ID
-
Synonyms
APCL
Documentation
Powered by Bioz
