ASF1A Antibody (YA4584)
(Synonyms: CIA; CGI-98; HSPC146)ASF1A Antibody (YA4584) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ASF1A.
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Host:
Mouse
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Isotype:
IgG1
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Application:
FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:200-1:400 | 1:10000 |
Product Details
ASF1A Antibody (YA4584) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ASF1A.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 23 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 23 kDa
Purified recombinant fragment of human ASF1A (AA: 1-204) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
ASF1A is an E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3. Plays a role in adenovirus-mediated cell lysis
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Subcellular Localization
Cytoplasm
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Isoforms & Post-Translational Modification
Q9H0Y0 has 2 isomers: Q9H0Y0-1: 25279 Da (predicted); Q9H0Y0-2: 14217 Da (predicted).
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Subunit
Interacts with MAP1LC3A. By interacting with MAP1LC3A, it plays a role in the conjugation of ATG12 to ATG5. Also able to directly interact either with ATG5 or ATG7 (By similarity). Interacts with IRGM
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SwissProt ID
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Synonyms
CIA; CGI-98; HSPC146
Documentation
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