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Cat. No.: HY-P84147A

ATF3 Antibody (YA3844)(PBS only)

Name: ATF3 Antibody (YA3844)(PBS only)
Brand: MedChemExpress
SKU: HY-P84147A
Availability: PreOrder

ATF3 Antibody (YA3844) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ATF3.

For research use only. We do not sell to patients.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	ICC/IF ICC/IF: Immunocytochemistry/ Immunofluorescence	FC FC: Flow Cytometry	ELISA ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio	1:200-1:1000	1:200-1:400	1:10000

Description

ATF3 Antibody (YA3844) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ATF3.

Host Mouse
Species Reactivity
Human
Observed Molecular Weight

Observed band size: 21 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 21 kDa

Immunogen

Purified recombinant fragment of human ATF3 (AA: 1-181) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Isotype

IgG1

Appearance

Liquid
Formulation

Supplied in PBS, pH 7.4.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

ATF3 is a This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter; Activates transcription presumably by sequestering inhibitory cofactors away from the promoters; Stress-induced isoform, counteracts the transcriptional repression of isoform 1
Subcellular Localization

Nucleus
Isoforms & Post-Translational Modification

P18847 has 5 isomers: P18847-1: 20576 Da (predicted); P18847-2: 13266 Da (predicted); P18847-3: 15250 Da (predicted); P18847-4: 12261 Da (predicted); P18847-5: 14314 Da (predicted).
Subunit

Binds DNA as a homodimer or a heterodimer. Interacts with KAT5; promoting KAT5 autoacetylation and KAT5 deubiquitination by USP7 (PubMed:25865756)
SwissProt ID

P18847
Gene ID

467 [NCBI]