CABP1 Antibody (YA6490)

Cat. No.: HY-P86797: Data Sheet User Guide for Antibodies
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CABP1 Antibody (YA6490) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CABP1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

CABP1 Antibody (YA6490) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CABP1.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 40 kDa;

Observed band size: 40 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q9NZU7

Gene ID

9478 [NCBI]

Immunogen

Synthetic peptide within Human CABP aa 150-250.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000
FC FC: Flow Cytometry	1:500-1:1000

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs) (PubMed:14570872). Inhibits agonist-induced intracellular calcium signaling (PubMed:15980432). Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels (PubMed:11865310). Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but has an opposite effect on channel function (PubMed:15140941). Suppresses the calcium-dependent inactivation of CACNA1D (By similarity). Inhibits TRPC5 channels (PubMed:15895247). Prevents NMDA receptor-induced cellular degeneration. Required for the normal transfer of light signals through the retina (By similarity)

Subcellular Localization：Cytoplasm, cytoskeleton,Cytoplasm, perinuclear region,Cell membrane,Golgi apparatus,Postsynaptic density,Cytoplasm, cytoskeleton,Cytoplasm, cell cortex,Cell membrane

Expression：
Tissue_Specificity: Retina and brain. Somatodendritic compartment of neurons. Calbrain was found exclusively in brain where it is abundant in the hippocampus, habenular area in the epithalamus and in the cerebellum

Isoforms & Post-Translational Modification：Q9NZU7 has four isomers: Q9NZU7-4: 39838 Da (predicted); Q9NZU7-1: 25979 Da (predicted); Q9NZU7-2: 19430 Da (predicted); Q9NZU7-3: 8139 Da (predicted).
Phosphorylated

Subunit：Homodimer; when bound to calcium or magnesium

Synonyms

CABP 1 antibody; CaBP1 antibody; CABP1_HUMAN antibody; Calbrain antibody; Calcium binding protein 1 antibody; Calcium binding protein 5 antibody; Calcium-binding protein 1 antibody; Caldendrin antibody; HCALB BR antibody; HCALB_BR antibody;

Documentation

User Guide for Antibodies (1077 KB)