CD163L1 Antibody (YA7663)
(Synonyms: CD163b, CD163B, M160, UNQ6434/PRO23202, CD163L1, Scavenger receptor cysteine-rich type 1 protein M160, CD163 antigen-like 1)
Based on 1 Customer Validation
CD163L1 Antibody (YA7663) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD163L1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
IHC-P, IHC-F, IF-Tissue, FC, ICC/IF
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Reactivity :
Human
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Formulation:
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IHC-F
IHC-F: Immunohistochemistry-Frozen
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IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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FC
FC: Flow Cytometry
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|---|---|
| Dilution Ratio | 1:200-1000 | 1:200-1000 | 1:200-1000 | 1:50-100 | 1:100-200 |
Product Details
CD163L1 Antibody (YA7663) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD163L1.
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Host Rabbit
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Clonality Recombinant
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Species ReactivityHuman Predicted Reactivity: Human
Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
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Observed Molecular WeightObserved band size: 160 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 159 kDa
A synthesized peptide derived from human CD163L1: 1400-1453.
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% glycerol.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD163L1 (CD163 molecule-like 1) is a type I transmembrane glycoprotein belonging to the scavenger receptor cysteine enrichment (SRCR) superfamily. CD163L1 is an endocytosis receptor that undergoes endocytosis via a clathrin-mediated pathway, a process that occurs spontaneously without receptor cross-linking. This suggests a role in clearing potentially harmful molecules from the tissue microenvironment and promoting inflammation resolution. CD163L1 is involved in the regulation of innate immunity and may function through the following mechanisms: recognizing and clearing damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs); participating in anti-inflammatory pathways associated with the recognition and clearance of apoptotic cells and pathogens, and regulating the intensity of the inflammatory response[1].
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Subcellular Localization
Cell membrane,Cell membrane,Secreted
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Expression
Tissue_Specificity: Isoform 1 is highly expressed in the spleen, lymph nodes, thymus, and fetal liver and weakly expressed in bone marrow and no expression was found in peripheral blood leukocytes. Isoform 1 expression is restricted to the monocyte and macrophage cell lines. Isoform 2 is only expressed in spleen -
Isoforms & Post-Translational Modification
CD163L1 has 4 isomers: Q9NR16-1: 159239 Da (predicted); Q9NR16-2: 155484 Da (predicted); Q9NR16-3: 79769 Da (predicted); Q9NR16-4: 160322 Da (predicted).
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SwissProt ID
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Synonyms
CD163b, CD163B, M160, UNQ6434/PRO23202, CD163L1, Scavenger receptor cysteine-rich type 1 protein M160, CD163 antigen-like 1
Documentation
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