CD172b Antibody (YA3485)(PBS only)

Cat. No.: HY-P83788A: Data Sheet User Guide for Antibodies
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CD172b Antibody (YA3485) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD172b.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

CD172b Antibody (YA3485) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD172b.

Host

Mouse

Molecular Weight

Predicted band size: 43.2 kDa;

Observed band size: 48 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

O00241

Gene ID

10326 [NCBI]

Immunogen

Purified recombinant fragment of human CD172b (AA: extra 72-309) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Also participates in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP (PubMed:10604985)

Subcellular Localization：Cell membrane; Single-pass type I membrane protein

Expression：
Tissue_specificity:Detected in monocytes and dendritic cells

Isoforms & Post-Translational Modification：O00241 has 3 isomers: O00241-1: 43211 Da (predicted); O00241-2: 19394 Da (predicted); Q5TFQ8-1: 43359 Da (predicted).
N-glycosylated

Subunit：Homodimer; disulfide-linked. Interacts with TYROBP. This interaction results in the recruitment of SYK

Synonyms

SIRPB1; SIRP-BETA-1

Documentation

User Guide for Antibodies (1077 KB)