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CD34 Antibody (YA3935)(PBS only)

(Synonyms: CD34, Hematopoietic progenitor cell antigen CD34)

CD34 Antibody (YA3935) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CD34.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2b

  • Application:

    WB, FC, ELISA

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • CD34 Antibody (YA3935)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:500-1:2000 1:200-1:400 1:10000

Product Details

Description

CD34 Antibody (YA3935) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CD34.

  • Host Mouse
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 120 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 41 kDa
Immunogen

Purified recombinant fragment of human CD34 (AA: extra 32-290) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Isotype

IgG2b

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    CD34 is a Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins

  • Subcellular Localization

    Membrane; Single-pass type I membrane protein

  • Expression


    Tissue_specificity:It is selectively expressed on hematopoietic progenitor cells and small vascular endothelial cells in various tissues.

  • Isoforms & Post-Translational Modification

    P28906 has 2 isomers: P28906-1: 40716 Da (predicted); P28906-2: 35011 Da (predicted).
    Highly glycosylated;Phosphorylated on serine residues by PKC

  • SwissProt ID

    P28906

  • Gene ID
    947 [NCBI]
  • Synonyms

    CD34, Hematopoietic progenitor cell antigen CD34

CD34 Antibody (YA3935)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • CD34 Antibody (YA3935)(PBS only) Product Image