EFNA2 (Ephrin A2) Antibody (YA8256)

Cat. No.: HY-P88572: Data Sheet User Guide for Antibodies
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EFNA2 (Ephrin A2) Antibody (YA8256) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to EFNA2 (Ephrin A2).

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

EFNA2 (Ephrin A2) Antibody (YA8256) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to EFNA2 (Ephrin A2).

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 21.3 kDa

Species Reactivity

Human

SwissProt ID

O43921

Immunogen

Full length human recombinant protein of human EFNA2 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2b

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. With the EPHA2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis (By similarity)

Subcellular Localization：Cell membrane

Isoforms & Post-Translational Modification：O43921: 213 amino acids, molecular weight 23878 Da.

Subunit：Binds to the receptor tyrosine kinases EPHA3, EPHA4 and EPHA5

Synonyms

ELF-1; EPLG6; HEK7-L; LERK-6; LERK6

Documentation

User Guide for Antibodies (1077 KB)