EFNA2 (Ephrin A2) Antibody (YA8256)
(Synonyms: ELF-1; EPLG6; HEK7-L; LERK-6; LERK6)EFNA2 (Ephrin A2) Antibody (YA8256) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to EFNA2 (Ephrin A2).
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Host:
Mouse
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Isotype:
IgG2b
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Application:
IHC-P, ICC/IF, FC
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100-250 | 1:100 |
Product Details
EFNA2 (Ephrin A2) Antibody (YA8256) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to EFNA2 (Ephrin A2).
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 21.3 kDa
Full length human recombinant protein of human EFNA2 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
EFNA2 cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. With the EPHA2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis
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Subcellular Localization
Cell membrane
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Isoforms & Post-Translational Modification
O43921: 213 amino acids, molecular weight 23878 Da.
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Subunit
Binds to the receptor tyrosine kinases EPHA3, EPHA4 and EPHA5
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SwissProt ID
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Synonyms
ELF-1; EPLG6; HEK7-L; LERK-6; LERK6
Documentation
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