Ephrin A2
Ephrin-A2 (EFNA2) is a GPI-anchored A-class ephrin that engages multiple EphA receptors, including EphA3, EphA4, EphA5 and EphA7. It is best known for topographic mapping of the retina onto the superior colliculus, where graded expression along the nasal-temporal axis helps position retinal ganglion cell axons. In hippocampus and cortex, ephrin-A2 regulates axon guidance, dendritic spine morphology and synaptic plasticity, acting in part through reverse signaling into the ligand-expressing cell. Ephrin-A2 also influences neural crest cell migration and has been implicated in tumor angiogenesis. Recombinant ephrin-A2 is commonly used as a clustering-competent ligand to activate EphA receptors in binding and signaling studies.
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Ephrin A2 Recombinant Proteins (3)
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
