HLA-DR Antibody (YA3613)
(Synonyms: MLRW; HLA-DRA1)HLA-DR Antibody (YA3613) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to HLA-DR.
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Host:
Mouse
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Isotype:
IgG2b
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Application:
WB, ICC/IF, FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:100-1:500 | 1:200-1:400 | 1:10000 |
Product Details
HLA-DR Antibody (YA3613) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to HLA-DR.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 29 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 29 kDa
Purified recombinant fragment of human HLA-DRA (AA: 26-254) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
HLA-DR is a heterodimeric transmembrane glycoprotein composed of two non-covalently linked chains: an α chain and a β chain. HLA-DR is primarily expressed on the surface of professional antigen-presenting cells (APCs). It functions in antigen presentation and coordinates T-cell activation and differentiation, thereby facilitating the generation of an effective immune response.
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Subcellular Localization
Cell membrane; Single-pass type I membrane protein; Endoplasmic reticulum membrane; Single-pass type I membrane protein; Early endosome membrane; Single-pass type I membrane protein; Late endosome membrane; Single-pass type I membrane protein; Lysosome membrane; Single-pass type I membrane protein; Autolysosome membrane; Single-pass type I membrane protein
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Expression
Tissue_specificity:Expressed in professional APCs: macrophages, dendritic cells and B cells (at protein level). Expressed in thymic epithelial cells (at protein level)
Induction:Up-regulated in dendritic cells upon maturation -
Subunit
Heterotrimer that consists of an alpha chain HLA-DRA, a beta chain HLA-DRB and a peptide (peptide-MHCII)
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SwissProt ID
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Synonyms
MLRW; HLA-DRA1
Documentation
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