Integrin alpha 2 Antibody (YA3834)(PBS only)

Cat. No.: HY-P84137A: Data Sheet User Guide for Antibodies
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Integrin alpha 2 Antibody (YA3834) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Integrin alpha 2.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Integrin alpha 2 Antibody (YA3834) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Integrin alpha 2.

Host

Mouse

Molecular Weight

Predicted band size: 129 kDa;

Observed band size: 150 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P17301

Gene ID

3673 [NCBI]

Immunogen

Purified recombinant fragment of human CD49B (AA: extra 994-1132) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-1:500
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix; (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human rotavirus A; (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human echoviruses 1 and 8

Subcellular Localization：Membrane; Single-pass type I membrane protein

Subunit：Heterodimer of an alpha and a beta subunit. Alpha-2 associates with beta-1. Interacts with HPS5 and RAB21

Synonyms

ITGA2; BR; GPIa; HPA-5; VLA-2; VLAA2

Documentation

User Guide for Antibodies (1077 KB)