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Integrin alpha 2 Antibody (YA3834)(PBS only)

(Synonyms: ITGA2; BR; GPIa; HPA-5; VLA-2; VLAA2)

Integrin alpha 2 Antibody (YA3834) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Integrin alpha 2.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    ICC/IF, FC, ELISA

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • Integrin alpha 2 Antibody (YA3834)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:100-1:500 1:200-1:400 1:10000

Product Details

Description

Integrin alpha 2 Antibody (YA3834) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Integrin alpha 2.

  • Host Mouse
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 150 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 129 kDa
Immunogen

Purified recombinant fragment of human CD49B (AA: extra 994-1132) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Integrin alpha 2 is an Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix; (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human rotavirus A; (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human echoviruses 1 and 8

  • Subcellular Localization

    Membrane; Single-pass type I membrane protein

  • Subunit

    Heterodimer of an alpha and a beta subunit. Alpha-2 associates with beta-1. Interacts with HPS5 and RAB21

  • SwissProt ID

    P17301

  • Gene ID
    3673 [NCBI]
  • Synonyms

    ITGA2; BR; GPIa; HPA-5; VLA-2; VLAA2

Integrin alpha 2 Antibody (YA3834)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • Integrin alpha 2 Antibody (YA3834)(PBS only) Product Image