KIFAP3 Antibody (YA2769)
(Synonyms: KAP3; KIF3AP; Kifap3; Kinesin associated protein 3; SMAP)KIFAP3 Antibody (YA2769) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to KIFAP3.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:100 | 1:50-1:200 | 1:50-1:100 |
Product Details
KIFAP3 Antibody (YA2769) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to KIFAP3.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 91-100 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 91 kDa
Entrez Gene: 22920 Human ; 16579 Mouse ;
SwissProt: Q92845 Human ; P70188 Mouse ; D3ZK15 Rat
OMIM: 601836 Human
A synthesized peptide derived from human KIFAP3 aa700-792/792.
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
KIFAP3 is involved in tethering the chromosomes to the spindle pole and in chromosome movement. Binds to the tail domain of the KIF3A/KIF3B heterodimer to form a heterotrimeric KIF3 complex and may regulate the membrane binding of this complex
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Isoforms & Post-Translational Modification
Q92845 has 4 isomers: Q92845-1: 91205 Da (predicted); Q92845-2: 86290 Da (predicted); Q92845-3: 86728 Da (predicted); Q92845-4: 82144 Da (predicted).
Phosphorylated on tyrosine residues by SRC in vitro; this reduces the binding affinity of the protein for RAP1GDS1 -
Subunit
Heterotrimer of KIFAP3, KIF3A and KIF3B. Interacts with RAP1GDS1/SMG GDS. Interacts with SMC3 subunit of the cohesin complex
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SwissProt ID
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Synonyms
KAP3; KIF3AP; Kifap3; Kinesin associated protein 3; SMAP
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Research Field
Epigenetics and Nuclear Signaling
Documentation
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