MetRS Antibody (YA3196)
(Synonyms: MRS; ILLD; CMT2U; ILFS2; METRS; MTRNS; SPG70)
Based on 1 Customer Validation
MetRS Antibody (YA3196) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MetRS.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, IHC-F, IHC-P, ICC/IF, FC, IP
-
Reactivity :
Human, Rat
-
Formulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
|
IP
IP: Immunoprecipitation
|
|---|---|---|---|---|---|
| Dilution Ratio | 1:1000-1:5000 | 1:500-1:2000 | 1:50-1:200 | 1:20-1:50 | 1:20-1:50 |
Product Details
MetRS Antibody (YA3196) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MetRS.
-
Host Rabbit
-
Clonality Recombinant,Monoclonal
-
Species ReactivityHuman, Rat
-
Observed Molecular WeightObserved band size: 101 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 101 kDa
Entrez Gene: 4141 Human ; 216443 Mouse ; 299851 Rat
SwissProt: P56192 Human ; Q68FL6 Mouse ;
OMIM: 615486 Human
A synthetic peptide of human MARS
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
-
Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
MetRS catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Plays a role in the synthesis of ribosomal RNA in the nucleolus[1][2].
-
Subcellular Localization
Cytoplasm, cytosol; Nucleus, nucleolus
-
Isoforms & Post-Translational Modification
P56192 has 2 isomers: P56192-1: 101116 Da (predicted); P56192-2: 61816 Da (predicted).
-
Subunit
Monomer (PubMed:11714285). Part of a multisubunit complex that groups tRNA ligases for Arg (RARS1), Asp (DARS1), Gln (QARS1), Ile (IARS1), Leu (LARS1), Lys (KARS1), Met (MARS1) the bifunctional ligase for Glu and Pro (EPRS1) and the auxiliary subunits AIMP1/p43, AIMP2/p38 and EEF1E1/p18 (PubMed:19131329, PubMed:19289464, PubMed:26472928, Ref.26). Forms a linear complex that contains MARS1, EEF1E1, EPRS1 and AIMP2 that is at the core of the multisubunit complex (PubMed:26472928)
-
SwissProt ID
-
Synonyms
MRS; ILLD; CMT2U; ILFS2; METRS; MTRNS; SPG70
-
Research Field
Signal Transduction
Documentation
Powered by Bioz
