2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies Flow Cytometry Antibodies
  5. NKp30 Antibody (YA1471)

NKp30 Antibody (YA1471)

Cat. No.: HY-P81726
User Guide for Antibodies Technical Support

NKp30 Antibody (YA1471) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NKp30.

For research use only. We do not sell to patients.

Size Price Stock Quantity
20 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 μL   Get quote  
Synthetic products have potential research and development risk.
or Bulk Inquiry

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

NKp30 Antibody (YA1471) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NKp30.
Host

Rabbit
Clonality

Recombinant, Monoclonal
Molecular Weight
Predicted band size: 22 kDa;
Observed band size: 22 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

Recombinant human NKp30 protein
Application &
Dilution Ratio
Application Dilution Ratio
FC
FC: Flow Cytometry
1:50-1:100
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
1:10000
Sensitivity Endogenous Purity Affinity Chromatography
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in sterile PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation
Subcellular Localization：Cell membrane; Single-pass type I membrane protein
Expression：
Tissue_specificity:It is selectively expressed in all resting and activated NK cells, with weaker expression in the spleen.
Isoforms & Post-Translational Modification：O14931 has 6 isomers: O14931-1: 21593 Da (predicted); O14931-2: 20640 Da (predicted); O14931-3: 19237 Da (predicted); O14931-4: 18749 Da (predicted); O14931-5: 17796 Da (predicted); O14931-6: 16393 Da (predicted).
Subunit：Homodimer in the unliganted form (PubMed:21422170, PubMed:21444796). Interacts with CD3Z (PubMed:10562324, Ref.2). Interacts with and is activated by binding to NCR3LG1 (PubMed:19528259, PubMed:21422170, PubMed:21444796). Interacts with and is activated by binding to BAG6 (PubMed:18055229, PubMed:18852879). Interacts with and is inhibited by binding to LGALS3 (PubMed:25315772)
Database

Entrez Gene: 259197 Human

SwissProt: O14931 Human

OMIM: 609148 Human

Research Field

Immunology
Synonyms
NCR3; CD337; NKp30; 1C7; LY117; MALS
Documentation
User Guide for Antibodies (1077 KB)

NKp30 Antibody (YA1471) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
NKp30 Antibody (YA1471)
Cat. No.:
HY-P81726
Quantity:
MCE Japan Authorized Agent:

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Country or Region *

Email Address *

     

Phone Number *

 

Organization Name *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.