PD-L2 Antibody (YA1348)

製品番号: HY-P81603: データシート User Guide for Antibodies
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PD-L2 Antibody (YA1348) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PD-L2.

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容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

おすすめ:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

PD-L2 Antibody (YA1348) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PD-L2.

Host

Rabbit

Clonality

Recombinant, Monoclonal

分子量

Predicted band size: 32 kDa;

Observed band size: 50-70 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q9BQ51

Gene ID

80380 [NCBI]

Immunogen

Recombinant human PDL2 protein

Application &
Dilution Ratio

Application	Dilution Ratio
FC FC: Flow Cytometry	1:50-1:100
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Sensitivity	Endogenous	純度	Affinity Chromatography
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity)

Subcellular Localization：Secreted; Endomembrane system; Single-pass type I membrane protein; Cell membrane; Single-pass type I membrane protein

Expression：
Tissue_specificity:It is highly expressed in the heart, placenta, pancreas, lungs, and liver, and lowly expressed in the spleen, lymph nodes, and thymus.

Induction:Up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL4/interleukin-4

Isoforms & Post-Translational Modification：Q9BQ51 has 3 isomers: Q9BQ51-1: 30957 Da (predicted); Q9BQ51-2: 20867 Da (predicted); Q9BQ51-3: 20745 Da (predicted).

Subunit：Interacts with PDCD1

Database

Entrez Gene: 80380 Human

SwissProt: Q9BQ51 Human

OMIM: 605723 Human

Research Field

Immunology

Synonyms

PD-1 ligand 2; PD-L2; PDCD1 ligand 2; B7-DC; CD273

ドキュメンテーション

User Guide for Antibodies (1077 KB)