Plastin L Antibody (YA1942)

Cat. No.: HY-P82197: Data Sheet COA
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User Guide for Antibodies
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Plastin L Antibody (YA1942) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Plastin L.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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Plastin L Antibody (YA1942) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation
References

Description

Plastin L Antibody (YA1942) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Plastin L.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 70 kDa;

Observed band size: 70 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P13796

Gene ID

3936 [NCBI]

Immunogen

A synthesized peptide derived from human Plastin L aa150-200/627.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-1:200
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200

Sensitivity	Endogenous	Purity	Affinity Chromatography
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in rabbit IgG in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Actin-binding protein (PubMed:16636079, PubMed:17294403, PubMed:28493397). Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28 (PubMed:17294403). Modulates the cell surface expression of IL2RA/CD25 and CD69 (PubMed:17294403)

Subcellular Localization：Cytoplasm, cytoskeleton; Cell junction; Cell projection; Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side

Expression：
Tissue_specificity:Detected in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia, in spleen and other lymph node-containing organs. Expressed in peripheral blood T-lymphocytes, neutrophils, monocytes, B-lymphocytes, and myeloid cells

Isoforms & Post-Translational Modification：P13796 has 2 isomers: P13796-1: 70288 Da (predicted); P13796-2: 21792 Da (predicted).
Phosphorylated on a serine residue in response to costimulation through TCR/CD3 and CD2 or CD28. Serine phosphorylation promotes association with the actin cytoskeleton and targeting to peripheral cell projections

Subunit：Monomer. Interacts with AIF1 (By similarity). Interacts with actin (PubMed:28493397)

Database

Entrez Gene: 3936 Human ; 18826 Mouse ; 306071 Rat

SwissProt: P13796 Human ; Q61233 Mouse ;

OMIM: 153430 Human

Research Field

Signal Transduction

Synonyms

CP64; L plastin; LC64P; LCP1; LPL; Lplastin; Plastin 2; PLS2

Documentation

Select Batch:

Data Sheet (234 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/hct-116-cell.html [Content Brief]

Plastin L Antibody (YA1942) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Plastin L Antibody (YA1942)

Plastin L Antibody (YA1942) Featured Recommendations:

Product Detail

Background

Documentation

References

Plastin L Antibody (YA1942) Related Classifications

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