PTPRD Antibody (YA3893)
(Synonyms: HPTP; PTPD; HPTPD; HPTPDELTA; RPTPDELTA)PTPRD Antibody (YA3893) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PTPRD.
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Host:
Mouse
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Isotype:
IgG1
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Application:
FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:200-1:400 | 1:10000 |
Product Details
PTPRD Antibody (YA3893) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PTPRD.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 175 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 214.8 kDa
Purified recombinant fragment of human PTPRD (AA: extra 1077-1265) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PTPRD is a Can bidirectionally induce pre- and post-synaptic differentiation of neurons by mediating interaction with IL1RAP and IL1RAPL1 trans-synaptically. Involved in pre-synaptic differentiation through interaction with SLITRK2
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Subcellular Localization
Membrane; Single-pass type I membrane protein
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Isoforms & Post-Translational Modification
P23468 has 7 isomers: P23468-1: 214760 Da (predicted); P23468-2: 212133 Da (predicted); P23468-3: 156088 Da (predicted); P23468-4: 169474 Da (predicted); P23468-5: 169606 Da (predicted); P23468-6: 169693 Da (predicted); P23468-7: 169277 Da (predicted).
A cleavage occurs, separating the extracellular domain from the transmembrane segment. This process called 'ectodomain shedding' is thought to be involved in receptor desensitization, signal transduction and/or membrane localization -
Subunit
Interacts with PPFIA1, PPFIA2 and PPFIA3 (PubMed:9624153). Interacts (via extracellular domain) with SLITRK4 (via LRR 1 and 2 repeats). Interacts with SLITRK2; induces presynaptic differentiation. Interacts (via the second immunoglobilin domain) with IL1RAPL1 (via the first immunoglobilin domain); induces pre- and postsynaptic differentiation of neurons and synapse formation. Interacts (via the third immunoglobilin domain) with IL1RAP (via the first immunoglobilin domain); induces pre- and postsynaptic differentiation of neurons (By similarity)
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SwissProt ID
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Synonyms
HPTP; PTPD; HPTPD; HPTPDELTA; RPTPDELTA
Documentation
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