SF20 Antibody (YA2528)
(Synonyms: IL25; IL27; SF20; IL27w; C19orf10; R33729_1; EUROIMAGE1875335)SF20 Antibody (YA2528) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SF20.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, FC
-
Reactivity :
Human
-
Formulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
FC
FC: Flow Cytometry
|
|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:20-1:50 |
Product Details
SF20 Antibody (YA2528) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SF20.
-
Host Rabbit
-
Clonality Recombinant,Monoclonal
-
Species ReactivityHuman
-
Observed Molecular WeightObserved band size: 19 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 19 kDa
Recombinant protein of human SF20 aa53-153.
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
SF20 is a Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. Involved in endothelial cell proliferation and angiogenesis[1].
-
Subcellular Localization
Secreted; Endoplasmic reticulum-Golgi intermediate compartment; Endoplasmic reticulum; Golgi apparatus
-
Expression
Tissue_specificity:Expressed in eosinophils (at protein level) (PubMed:29954947) . Expressed in bone marrow cells (PubMed:25581518) . Expressed in synovial tissue. Found in synovial fluid of with arthropaties (PubMed:17362502)
Induction:Up-regulated in response to myocardial infarction (MI) -
SwissProt ID
-
Synonyms
IL25; IL27; SF20; IL27w; C19orf10; R33729_1; EUROIMAGE1875335
-
Research Field
Cell Biology
Documentation
References
Powered by Bioz
