MYDGF - myeloid derived growth factor Gene
Also Known as IL25; IL27; SF20; IL27w; C19orf10; R33729_1; EUROIMAGE1875335
生物種: Homo sapiens
遺伝子タイプ: protein coding
遺伝子ID: 56005
About MYDGF
Cytogenetic location: 19p13.3
Genomic coordinates (GRCh38): 19:4,657,545-4,670,342 (from NCBI)
This gene has 4 transcripts (splice variants) and 183 orthologues. Ubiquitous expression in colon (RPKM 37.2), prostate (RPKM 33.6) and 25 other tissues.
Summary
The protein encoded by this gene was previously thought to support proliferation of lymphoid cells and was considered an interleukin. However, this activity has not been reproducible and the function of this protein is currently unknown. [provided by RefSeq, Jul 2008]
MYDGF Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_019107.4 | NP_061980.1 | myeloid-derived growth factor precursor |
| Molecular Function GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
25416956 | GOA |
| Biological Process GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| involved in positive regulation of angiogenesis |
IDA
IDA: Inferred from direct assay
|
25581518 | GOA |
| involved in positive regulation of endothelial cell proliferation |
IDA
IDA: Inferred from direct assay
|
25581518 | GOA |
| Cellular Component GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| located in Golgi apparatus |
IDA
IDA: Inferred from direct assay
|
29954947 | GOA |
| located in endoplasmic reticulum |
IDA
IDA: Inferred from direct assay
|
29954947 | GOA |
| located in extracellular space |
IDA
IDA: Inferred from direct assay
|
25581518 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
MYDGF Protein Structure
UPF0556
UPF0556: Uncharacterised protein family UPF0556 (16 - 173)
- 0
- 100
- 173 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
myeloid-derived growth factor |
|
MYDGF Protein-protein interaction Information
|
Type
|
タンパク質名 | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | 参考文献 |
|---|---|---|---|---|---|---|---|
|
Intra
|
MYDGF | Q969H8 | ACOT13 | Homo sapiens | Q9NPJ3 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | ACOT13 | Homo sapiens | Q9NPJ3 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | ACOT13 | Homo sapiens | Q9NPJ3 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | LCN2 | Homo sapiens | P80188 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | LCN2 | Homo sapiens | P80188 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | HPCA | Homo sapiens | P84074 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | HPCA | Homo sapiens | P84074 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | LDB2 | Homo sapiens | O43679 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | LDB2 | Homo sapiens | O43679 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | SGTA | Homo sapiens | O43765 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | SGTA | Homo sapiens | O43765 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | SGTA | Homo sapiens | O43765 | 25416956 | |
|
Intra
|
MYDGF | Q969H8 | EIF3F | Homo sapiens | O00303 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | EIF3F | Homo sapiens | O00303 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | UBQLN1 | Homo sapiens | Q9UMX0 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | UBQLN1 | Homo sapiens | Q9UMX0 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | UBQLN1 | Homo sapiens | Q9UMX0 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | DDIT4L | Homo sapiens | Q96D03 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | DDIT4L | Homo sapiens | Q96D03 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | DDIT4L | Homo sapiens | Q96D03 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | SGTB | Homo sapiens | Q96EQ0 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | SGTB | Homo sapiens | Q96EQ0 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | SGTB | Homo sapiens | Q96EQ0 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | HPCAL1 | Homo sapiens | P37235 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | HPCAL1 | Homo sapiens | P37235 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | HPCAL1 | Homo sapiens | P37235 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | NCALD | Homo sapiens | P61601 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | NCALD | Homo sapiens | P61601 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | UBQLN2 | Homo sapiens | Q9UHD9 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | UBQLN2 | Homo sapiens | Q9UHD9 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | UBQLN2 | Homo sapiens | Q9UHD9 | 32296183 | |
|
Intra
|
MYDGF | Q969H8 | PDIA5 | Homo sapiens | Q14554 | 33961781 |
Cross: Cross-species interaction
Intra: Intraspecies interaction
Recombinant MYDGF Proteins
| 製品番号 | 製品名 | アクセッション番号 | 純度 |
|---|---|---|---|
| HY-P70581 | MYDGF Protein, Human (His) | Q969H8 (S33-L173) | ≥ 95%, as determined by reducing SDS-PAGE. |
| HY-P700641 | SF20/MYDGF Protein, Human (HEK293, His) | Q969H8 (V32-L173) | ≥ 95%, as determined by reducing SDS-PAGE. |
MYDGF 抗体
| 製品番号 | 製品名 | アプリケーション | 反応性 |
|---|---|---|---|
| HY-P82783 | SF20 Antibody (YA2528) | WB, FC | Human |
| HY-P82783A | SF20 Antibody (YA2528)(PBS only) | WB, FC | Human |
関連疾患
| Diseases | Alias | |
|---|---|---|
| Myocardial Infarction |
|
|
| Heinz Body Anemias |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(4)
| 製品番号 | 製品名 |
製品効果
|
純度 |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS08889 | MYDGF Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-174576 | Human MYDGF mRNA | / | Unkown | |
| HY-RS17706 | Mydgf Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS24171 | Mydgf Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| 生物種 | Symbol | 由来 | ID |
|---|---|---|---|
| Mus musculus | MYDGF | MGD | MGI:2156020 |
| Bos taurus | MYDGF | VGNC | VGNC:31790 |
| Felis catus | MYDGF | VGNC | VGNC:63673 |
| Rattus norvegicus | MYDGF | RGD | RGD:1589603 |
| Canis familiaris | MYDGF | VGNC | VGNC:43532 |
| Others | MYDGF | NCBI |
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