SFT Antibody (YA3238)(PBS only)
(Synonyms: ubiquitin conjugating enzyme E2 D1; SFT; UBCH5; UBC4/5; UBCH5A; E2(17)KB1)SFT Antibody (YA3238) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SFT.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, FC, IP
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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IP
IP: Immunoprecipitation
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|---|---|---|---|---|
| Dilution Ratio | 1:1000-1:5000 | 1:50-1:100 | 1:10-1:100 | 1:10-1:100 |
Product Details
SFT Antibody (YA3238) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SFT.
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Host Rabbit
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 17 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 17 kDa
A synthetic peptide of human SFT aa119-132.
Affinity Purified
Non-conjugated
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SFT is an Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1. Ubiquitinates STUB1-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4[1][2][3][4][5][6].
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Subcellular Localization
Cytoplasm
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Expression
Tissue_specificity:Ubiquitous. Up-regulated in livers of iron-overloaded with hereditary hemochromatosis -
Subunit
Component of a E3 ubiquitin ligase complex containing UBE2D1, SIAH1, CACYBP/SIP, SKP1, APC and TBL1X. Interacts with RNF11
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SwissProt ID
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Synonyms
ubiquitin conjugating enzyme E2 D1; SFT; UBCH5; UBC4/5; UBCH5A; E2(17)KB1
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Research Field
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Documentation
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