SLC2A5 (GLUT5) Antibody (YA7784)

Cat. No.: HY-P88100: Data Sheet User Guide for Antibodies
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SLC2A5 (GLUT5) Antibody (YA7784) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SLC2A5 (GLUT5).

For research use only. We do not sell to patients.

Size	Price	Stock
20 μL		Ask For Quote & Lead Time
50 μL		Ask For Quote & Lead Time
100 μL		Ask For Quote & Lead Time

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation
References

Description

SLC2A5 (GLUT5) Antibody (YA7784) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SLC2A5 (GLUT5).

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 54.8 kDa

Species Reactivity

Human

SwissProt ID

P22732

Immunogen

Full length human recombinant protein of human SLC2A5 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-250
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100
IP 2ug/500ul

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Functions as a fructose transporter that has only low activity with other monosaccharides (PubMed:16186102, PubMed:17710649, PubMed:28083649, PubMed:29548810, PubMed:8333543). Can mediate the uptake of 2-deoxyglucose, but with low efficiency (PubMed:1695905). Essential for fructose uptake in the small intestine (By similarity). Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose (By similarity). Required for the development of high blood pressure in response to high dietary fructose intake (By similarity)

Subcellular Localization：Apical cell membrane,Cell membrane,Cell membrane, sarcolemma

Expression：
Tissue_Specificity: Detected in skeletal muscle, and in jejunum brush border membrane and basolateral membrane (at protein level) (PubMed:7619085). Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue
Induction: By forskolin in Caco-2 cells

Isoforms & Post-Translational Modification：P22732 has two isomers: P22732-1: 54974 Da (predicted); P22732-2: 26519 Da (predicted).

Synonyms

GLUT-5; GLUT5

Documentation

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/hl-60-cell.html [Content Brief]