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TCTP Antibody (YA038)(PBS only)

(Synonyms: Translationally-controlled tumor protein; TCTP; Fortilin; Histamine-releasing factor; HRF; p23)

TCTP Antibody (YA038) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TCTP.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, ICC/IF, FC

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • TCTP Antibody (YA038)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
Dilution Ratio 1:1000-1:5000 1:200-1:500 1:100-1:1000

Product Details

Description

TCTP Antibody (YA038) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TCTP.

  • Host Rabbit
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 20 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 20 kDa
Immunogen

Synthetic peptide corresponding to Human TCTP.The exact sequence is proprietary to MCE.

Conjugation

Non-conjugated

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    TCTP is involved in calcium binding and microtubule stabilization. Acts as a negative regulator of TSC22D1-mediated apoptosis, via interaction with and destabilization of TSC22D1 protein[1][2][3][4].

  • Subcellular Localization

    Cytoplasm

  • Expression


    Tissue_specificity:Found in several healthy and tumoral cells including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, and lymphomas. It cannot be detected in kidney and renal cell carcinoma (RCC) . Expressed in placenta and prostate

    Induction:Down-regulated in response to enterovirus 71 (EV71) infection

  • Isoforms & Post-Translational Modification

    P13693 has 2 isomers: P13693-1: 19595 Da (predicted); P13693-2: 15597 Da (predicted).

  • Subunit

    Homodimer (By similarity). Interacts with STEAP3 (PubMed:15319436). Interacts with TSC22D1; interaction results in the destabilization of TSC22D1 protein (PubMed:18325344)

  • SwissProt ID

    P13693

  • Gene ID
    7178 [NCBI]
  • Synonyms

    Translationally-controlled tumor protein; TCTP; Fortilin; Histamine-releasing factor; HRF; p23

TCTP Antibody (YA038)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • TCTP Antibody (YA038)(PBS only) Product Image
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  • TCTP Antibody (YA038)(PBS only) Product Image