TNFRSF18 Antibody (YA4593)
(Synonyms: AITR; GITR; CD357; GITR-D)TNFRSF18 Antibody (YA4593) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TNFRSF18.
-
Host:
Mouse
-
Isotype:
IgG1
-
Application:
IHC-P, FC, ELISA
-
Reactivity :
Human
-
Formulation:
Supplied in PBS with 0.05% sodium azide
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
FC
FC: Flow Cytometry
|
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
|
|---|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:200-1:400 | 1:10000 |
Product Details
TNFRSF18 Antibody (YA4593) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TNFRSF18.
-
Host Mouse
-
Clonality Monoclonal
-
Species ReactivityHuman
-
Observed Molecular WeightObserved band size: 41 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 26 kDa
Purified recombinant fragment of human TNFRSF18 (AA: extra 26-162) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in PBS with 0.05% sodium azide
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
TNFRSF18 receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway
-
Subcellular Localization
Cell membrane; Single-pass type I membrane protein; Secreted
-
Expression
Tissue_specificity:It is expressed in lymph nodes and peripheral blood leukocytes, but its expression is weaker in the spleen.
Induction:Up-regulated in peripherical mononuclear cells after antigen stimulation/lymphocyte activation -
Subunit
Binds to TRAF1, TRAF2, and TRAF3, but not TRAF5 and TRAF6. Binds through its C-terminus to SIVA1/SIVA
-
SwissProt ID
-
Synonyms
AITR; GITR; CD357; GITR-D
Documentation
Powered by Bioz
