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  2. Primary Antibodies
  3. Toll-Like Receptor 3 Antibody

Toll-Like Receptor 3 Antibody

Cat. No.: HY-P80917
User Guide for Antibodies

Toll-Like Receptor 3 Antibody is a non-conjugated and Mouse origined monoclonal antibody about 105 kDa, targeting to Toll-Like Receptor 3 . It can be used for WB, IHC-P, IHC-F, IF, ELISA assays with tag free, in the background of Human, Mouse, Rat.

For research use only. We do not sell to patients.

Size Price Stock Quantity
Free Sample   Apply now  
10 μL $70 In-stock
50 μL $185 In-stock
100 μL $300 In-stock
250 μL   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Toll-Like Receptor 3 Antibody is a non-conjugated and Mouse origined monoclonal antibody about 105 kDa, targeting to Toll-Like Receptor 3 . It can be used for WB, IHC-P, IHC-F, IF, ELISA assays with tag free, in the background of Human, Mouse, Rat.

Background

Toll-Like Receptor 3 (2F10): The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It thus plays a role in host defense against multiple viruses. [provided by RefSeq, Jul 2021]

Tag

Free

Gene ID

7098

Synonyms
CD283; CD283 antigen; IIAE2; TLR 3; Tlr3; TLR3_HUMAN; Toll Like Receptor 3; Toll-like receptor 3.
Molecular Weight

Predicted band size: 105 kDa;Observed band size: 130 kDa

Purity

affinity purified

Conjugation

Non-conjugated

Research Field

Immunology

Product Categories

Primary Antibody; Rabbit Polyclonal Antibody

Host

Rabbit

Reactivity

Human, Mouse, Rat

SwissProt ID

O15455

Dilution Ratio

WB, IHC-P, IHC-F, IF, ELISA

Application

WB: 1:500-2000; IHC-P: 1:100-500; IHC-F: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000;

Appearance

Liquid

Formulation

Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Immunogen

KLH conjugated synthetic peptide derived from human TLR3: 801-905/905.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Toll-Like Receptor 3 Antibody
Cat. No.:
HY-P80917
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