VAV2 Antibody (YA3312)

Cat. No.: HY-P83567: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

VAV2 Antibody (YA3312) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VAV2.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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VAV2 Antibody (YA3312) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

VAV2 Antibody (YA3312) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VAV2.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 101 kDa;

Observed band size: 101 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P52735

Gene ID

7410 [NCBI]

Immunogen

A synthetic peptide of human VAV2

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:5000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-1:200
FC FC: Flow Cytometry	1:200-1:1000
IP IP: Immunoprecipitation	1:20
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:100

Sensitivity	Endogenous	Purity	Affinity Purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity)

Expression：
Tissue_specificity:Widely expressed

Isoforms & Post-Translational Modification：P52735 has 3 isomers: P52735-1: 101289 Da (predicted); P52735-2: 100057 Da (predicted); P52735-3: 97032 Da (predicted).
Phosphorylated on tyrosine residues in response to FGR activation

Subunit：Interacts (via SH2 domains) with the phosphorylated form of EPHA2. Interacts with SSX2IP (By similarity). Interacts with NEK3 and PRLR and this interaction is prolactin-dependent

Database

Entrez Gene: 7410 Human

SwissProt: P52735 Human

OMIM: 600428 Human

Research Field

Signal Transduction

Synonyms

VAV2; Vav 2 oncogene; VAV-2

Documentation

Select Batch:

Data Sheet (234 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

VAV2 Antibody (YA3312) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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VAV2 Antibody (YA3312)

VAV2 Antibody (YA3312) Featured Recommendations:

Product Detail

Background

Documentation

VAV2 Antibody (YA3312) Related Classifications

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