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Cat. No.: HY-12720B

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Apraclonidine dihydrochloride

(Synonyms: ALO 2145 dihydrochloride)

3 Cited Publications

Customer Review

Based on 3 publication(s) in Google Scholar

Apraclonidine (ALO 2145) dihydrochloride, a selective α2 and weak α1 receptor agonist activity, effectively low intraocular pressure (IOP) in eyes. Apraclonidine dihydrochloride is a topical ophthalmic solution.

For research use only. We do not sell to patients.

CAS No.: 73217-88-6
Formula: C₉H₁₂Cl₄N₄
Molecular Weight:318.03

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Apraclonidine dihydrochloride Chemical Structure

CAS No.: 73217-88-6

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Fluorescent Dye

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Biological Activity

Description

All Adrenergic Receptor Isoforms :

Chemical Information

CAS No. 73217-88-6
Molecular Weight 318.03
Formula C₉H₁₂Cl₄N₄
SMILES

NC1=CC(Cl)=C(NC2=NCCN2)C(Cl)=C1.[H]Cl.[H]Cl
Synonyms

ALO 2145 dihydrochloride
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (3)

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Anal Chim Acta

Bifunctional Ti4+-modified paper for selective extraction or removal of phospholipids and paper spray mass spectrometry for bioanalysis in urine and plasma. [Abstract]

2023 Oct 16:1278:341673. PMID: 37709425
Anal Lett

2022: 1-11.
bioRxiv

2026 Mar 7.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wijemanne S, et, al. Apraclonidine in the treatment of ptosis. J Neurol Sci. 2017 May 15:376:129-132. [Content Brief]

[2]. Searles RV, et al. Aqueous humor dynamics in anesthetized rats infused with intracameral apraclonidine. Pharmacology. 1999 Apr;58(4):220-6. [Content Brief]

[3]. Hayasaka Y, et al. Effects of topical antiglaucoma eye drops on prostaglandin E(2)-induced aqueous flare elevation in pigmented rabbits. Invest Ophthalmol Vis Sci. 2002 Apr;43(4):1142-5. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Apraclonidine dihydrochloride

3 Cited Publications

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Apraclonidine dihydrochloride

Publications Citing Use of MedChemExpress (MCE) Apraclonidine dihydrochloride

All Adrenergic Receptor Isoforms

Biological Activity

Chemical Information

Publications (3)

Purity & Documentation

References

Calculators

Help & FAQs

Apraclonidine dihydrochloride Related Classifications

HY-12720B Related Classifications