Ltbp2 - latent transforming growth factor beta binding protein 2 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16997

Summary

Predicted to enable microfibril binding activity. Acts upstream of or within supramolecular fiber organization. Located in collagen-containing extracellular matrix. Is expressed in several structures, including cardiovascular system; connective tissue; genitourinary system; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in Weill-Marchesani syndrome. Orthologous to human LTBP2 (latent transforming growth factor beta binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Ltbp2 Products (2)

mRNA Protein Name
NM_001370743.1 NP_001357672.1 latent-transforming growth factor beta-binding protein 2 isoform 1 precursor
NM_013589.4 NP_038617.4 latent-transforming growth factor beta-binding protein 2 isoform 2 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within supramolecular fiber organization IMP
IMP: Inferred from mutant phenotype
24908666 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

latent-transforming growth factor beta-binding protein 2

  • LTBP-2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS26205 Ltbp2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07878 LTBP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07879 LTBP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19709 Ltbp2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ltbp2 NCBI NCBI:4053