1. PROTAC PI3K/Akt/mTOR Cell Cycle/DNA Damage
  2. Target Protein Ligand-Linker Conjugates ATM/ATR
  3. ATR ligand 2-CO-Ph-COOH

ATR ligand 2-CO-Ph-COOH (Compound 39) is a Target Protein Ligand-Linker Conjugate that incorporates a ligand for ATR (HY-182017) and a PROTAC linker, which recruits E3 ligases. can be used for synthesis of PROTAC ATR degrader-3 (HY-182016).

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ATR ligand 2-CO-Ph-COOH

ATR ligand 2-CO-Ph-COOH Estructura química

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Descripciòn

ATR ligand 2-CO-Ph-COOH (Compound 39) is a Target Protein Ligand-Linker Conjugate that incorporates a ligand for ATR (HY-182017) and a PROTAC linker, which recruits E3 ligases. can be used for synthesis of PROTAC ATR degrader-3 (HY-182016)[1].

Peso molecular

483.52

Fòrmula

C27H25N5O4

SMILES

C[C@@H]1COCCN1C2=C3C(CN(C3)C(C4=CC=C(C=C4)C(O)=O)=O)=NC(C5=CC=CC6=C5C=CN6)=N2

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
ATR ligand 2-CO-Ph-COOH
Cat. No.:
HY-182018
Cantidad:
MCE Japan Authorized Agent: