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Referencia número: HY-182017

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ATR ligand 2

ATR ligand 2 (Compound 26) is a ATR PROTAC ligand. ATR ligand 2 can be conjugated with E3 ligase Ligand (HY-W077589A) and linker to synthesize PROTAC ATR degrader-3 (HY-182016).

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No. CAS: 3060178-60-8
Fòrmula: C₁₉H₂₁N₅O
Peso molecular:335.40

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

ATR ligand 2 Chemical Structure

No. CAS: 3060178-60-8

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Descripciòn

ATR ligand 2 (Compound 26) is a ATR PROTAC ligand. ATR ligand 2 can be conjugated with E3 ligase Ligand (HY-W077589A) and linker to synthesize PROTAC ATR degrader-3 (HY-182016)^[1].

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^[1]

ATR

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Chemical Information

No. CAS 3060178-60-8
Peso molecular 335.40
Fòrmula C₁₉H₂₁N₅O
SMILES

C[C@H]1N(C2=C3C(CNC3)=NC(C4=CC=CC5=C4C=CN5)=N2)CCOC1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Mao N D, et al. Design and Synthesis of Pyrrolo [3, 4-d] pyrimidine-Based ATR Degraders for Effective Treatment of Colorectal Cancer in Mouse Model[J]. Journal of Medicinal Chemistry, 2026. [Content Brief]

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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ATR ligand 2

Ver todos los productos específicos de isoformas ATM/ATR

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ATR ligand 2 Related Classifications

HY-182017 Related Classifications

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