1 Result for "

(1R)-cis-Bifenthrin

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "(1R)-cis-Bifenthrin" in MCE Product Catalog:

Cat. No.: HY-B0824A
CAS No.: 439680-76-9
Target:  

Autophagy

Research Areas:  

Others

(1R)-cis-Bifenthrin is a widely used pyrethroid pesticide with activity that reduces motor coordination. (1R)-cis-Bifenthrin has a significant impact on the motor function of ParKin-/- mice, as shown by increased pole climbing time and wheel running Time decreases. Exposure of (1R)-cis-Bifenthrin resulted in a significant reduction in tyrosine hydroxylase-positive cell counts and protein expression. (1R)-cis-Bifenthrin caused increased expression of mitophagy-related proteins LC3B and p62. (1R)-cis-Bifenthrin has a lower binding energy with transferrin and transferrin receptor 2, showing stronger interactions. The biological effects of (1R)-cis-Bifenthrin show relationships with mitophagy and ferroptosis-related pathways [1].
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