Colorectal mutant cancer protein
Definition:
References:
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[1]. Laurent Pangon, et al. MCC inhibits beta-catenin transcriptional activity by sequestering DBC1 in the cytoplasm. Int J Cancer. 2015 Jan 1;136(1):55-64. [Content Brief]
[2]. Camille Arnaud, et al. MCC, a new interacting protein for Scrib, is required for cell migration in epithelial cells. FEBS Lett. 2009 Jul 21;583(14):2326-32. [Content Brief]
[3]. Laurent Pangon, et al. The PDZ-binding motif of MCC is phosphorylated at position -1 and controls lamellipodia formation in colon epithelial cells. Biochim Biophys Acta. 2012 Jun;1823(6):1058-67. [Content Brief]
[4]. R Fukuyama, et al. Mutated in colorectal cancer, a putative tumor suppressor for serrated colorectal cancer, selectively represses beta-catenin-dependent transcription. Oncogene. 2008 Oct 9;27(46):6044-55. [Content Brief]