AMRI-59
AMRI-59 is a potent inhibitor of PrxI used for parasitic infections. AMRI-59 can increase cellular ROS, leading to activation of signaling pathways mediated by mitochondria and apoptosis signal-regulated kinase 1, thereby leading to apoptosis in A549 human lung adenocarcinoma. AMRI-59 exhibits significant antitumor activity without apparent acute toxicity.
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- CAS No.: 923515-92-8
- Formule: C25H27N3O2
- Masse moléculaire:401.50
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
PrxI[1]
Chemical Information
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CAS No. 923515-92-8
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Masse moléculaire 401.50
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Formule C25H27N3O2
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SMILES
O=C(N1CCC(CC2=CC=C(N3C=CC=C3)C=C2)CC1)NC4=CC=CC(C(C)=O)=C4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)