2915650-86-9
2915650-86-9
Chemical Structure
PARP-2-IN-3
- CAS No.: 2915650-86-9
- Formula:C20H20ClN3O3
- Molecular Weight:385.84
IUPAC Name: N-(4-(5-chlorobenzo[d]oxazol-2-yl)phenyl)-3-morpholinopropanamide
InChIKey: YUAYKEBADVSFNL-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C2=NC3=CC(Cl)=CC=C3O2)C=C1)CCN4CCOCC4
Biological Activity: PARP-2-IN-3 (Compound 12) is a potent PARP-2 inhibitor with an IC50 of 0.07 μM. PARP-2-IN-3 induces apoptosis and necrosis in cancer cells. PARP-2-IN-3 shows appropriate predicted pharmacokinetic parameters and oral bioavailability[1].
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PARP-2-IN-3 | PARP-2-IN-3 (Compound 12) is a potent PARP-2 inhibitor with an IC50 of 0.07 μM. PARP-2-IN-3 induces apoptosis and necrosis in cancer cells. PARP-2-IN-3 shows appropriate predicted pharmacokinetic parameters and oral bioavailability. | |||||||||||||||||||||
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