4484-88-2
Chemical Structure
α,α-Trehalose 6-phosphate
Synonym(s): Tre6P
- CAS No.: 4484-88-2
- Formula:C12H23O14P
- Molecular Weight:422.28
IUPAC Name: ((2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)methyl dihydrogen phosphate
InChIKey: LABSPYBHMPDTEL-LIZSDCNHSA-N
SMILES: O=P(O)(O)OC[C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@@H]1O[C@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO
Biological Activity: α,α-Trehalose 6-phosphate (Tre6P) is a glucose analogue with potent anti-hyperglcaemic activity. α,α-Trehalose 6-phosphate is rapidly converted to the end product, α,α′-trehalose, through the action of α,α-Trehalose 6-phosphate phosphatase (T6PP)[1][2].
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α,α-Trehalose 6-phosphate | α,α-Trehalose 6-phosphate (Tre6P) is a glucose analogue with potent anti-hyperglcaemic activity. α,α-Trehalose 6-phosphate is rapidly converted to the end product, α,α′-trehalose, through the action of α,α-Trehalose 6-phosphate phosphatase (T6PP). | |||||||||||||||||||||
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References
- [1]. Liu,Chunliang, et al. An improved method for the large scale preparation of alpha,alpha'-trehalose-6-phosphate.Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry, 2015, 56(23):3008-3010.
- [2]. Oke JM, et al. Hypoglycaemic activity of alpha, alpha trehalose-6-phosphate. Afr J Med Med Sci. 1998 Sep-Dec;27(3-4):219-23. [Content Brief]
