6961-46-2
6961-46-2
Chemical Structure
Idrocilamide
Synonym(s): LCB29
- CAS No.: 6961-46-2
- Formula:C11H13NO2
- Molecular Weight:191.23
IUPAC Name: N-(2-hydroxyethyl)cinnamamide
InChIKey: OSCTXCOERRNGLW-VOTSOKGWSA-N
SMILES: O=C(NCCO)/C=C/C1=CC=CC=C1
Biological Activity: Idrocilamide (LCB29) exhibits a muscle relaxing effect, that inhibits muscle twitch, tetanic tension, K+-induced as well as voltage clamp-induced contraction of rat soleus muscle fibers. Idrocilamide is also a caffeine antagonist, inhibiting the breakdown and biotransformation of caffeine[1][2].
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Idrocilamide | Idrocilamide (LCB29) exhibits a muscle relaxing effect, that inhibits muscle twitch, tetanic tension, K+-induced as well as voltage clamp-induced contraction of rat soleus muscle fibers. Idrocilamide is also a caffeine antagonist, inhibiting the breakdown and biotransformation of caffeine. | |||||||||||||||||||||
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References
- [1]. Brazier JL, et al. Inhibition by idrocilamide of the disposition of caffeine. Eur J Clin Pharmacol. 1980 Jan;17(1):37-43. [Content Brief]
- [2]. Bouron A, et al., The direct depressant effect of LCB29 (idrocilamide) on mechanical tension of rat soleus muscle fibers. Can J Physiol Pharmacol. 1990 Dec;68(12):1503-9. [Content Brief]
