CDK4/6-IN-8
CDK4/6-IN-8 (Compound 7p) is a selective CDK4 and CDK6 inhibitor with IC50 values of 5.01 nM and 3.97 nM, respectively.
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- CAS No.: 2649120-22-7
- Formule: C18H18N6O5
- Masse moléculaire:398.37
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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CDK6 3.97 nM (IC50) |
CDK4 5.01 nM (IC50) |
CDK4/6-IN-8 (Compound 7p) (0-656.1 µM, 48 h) shows anti-breast cancer activity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:MCF-7
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Concentration:0.1, 0.3, 0.9, 2.7, 8.1, 24.3, 72.9, 218.7 and 656.1 µM
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Incubation Time:48 h
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Result:Inhibited cell viability with an IC50 of 2.8 μM.
Chemical Information
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CAS No. 2649120-22-7
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Masse moléculaire 398.37
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Formule C18H18N6O5
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SMILES
O=C(C1=CC=C([N+]([O-])=O)C=C1)NNC(N2CCC[C@@H]2C(NC3=CC=CN=C3)=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CDK4/6-IN-8 Related Classifications
HY-143258 Related Classifications
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