country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-N21794

Copy Link Print Information

Dendrobine-N-oxide

Dendrobine-N-oxide is a dendrobine-type sesquiterpene alkaloid. It is isolated from Dendrobium nobile. Dendrobine-N-oxide inhibits neuroinflammation, reduces β-Amyloid accumulation, enhances the expression of neurotrophic factors, suppresses the hyperphosphorylation of Tau protein, and exerts anti-neuronal Apoptosis effects. Dendrobine-N-oxide shows no anticancer activity against colon cancer and pancreatic adenocarcinoma. It is used in research on neurodegenerative diseases.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 40072-57-9
Formule: C₁₆H₂₅NO₃
Masse moléculaire:279.37

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Dendrobine-N-oxide Chemical Structure

CAS No.: 40072-57-9

Stock

Quantité

Amount: USD 0.00

* Veuillez sélectionner la quantité avant d'ajouter des articles.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC50	>50 μM	Cytotoxicity against human HCT-116 colon tumour cells measured by MTT assay. Cytotoxicity against human HCT-116 colon tumour cells measured by MTT assay.	34930072
SW1990	IC50	>50 μM	Cytotoxicity against human SW1990 pancreatic tumour cells measured by MTT assay. Cytotoxicity against human SW1990 pancreatic tumour cells measured by MTT assay.	34930072

In Vitro

Dendrobine-N-oxide (up to 50 μM) exhibits no cytotoxic activity against human HCT-116 and SW1990 cell lines, with IC₅₀ values exceeding 50 μM^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 40072-57-9
Masse moléculaire 279.37
Formule C₁₆H₂₅NO₃
SMILES

C[C@@]12[C@@]3([H])[C@@]4([H])[C@H]([C@@](C(O4)=O)([H])[C@]1([H])CC[C@]2([H])C[N+]3([O-])C)C(C)C
Structure Classification
- Alkaloids
- Other Alkaloids
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Yang C, et al. Research Progress on the Alkaloids of Dendrobium nobile: Substantiation, Key Components, Pharmacological Activity, and Biosynthetic Pathways. Curr Issues Mol Biol. 2026 May 29;48(6):570.

[2]. Liu Q, et al. Metabolic profiling, in-situ spatial distribution, and biosynthetic pathway of functional metabolites in Dendrobium nobile stem revealed by combining UPLC-QTOF-MS with MALDI-TOF-MSI. Front Plant Sci. 2023 Jan 12;13:1125872.

[3]. Zhang MS, et al. Dendrobine-type alkaloids from Dendrobium nobile. Nat Prod Res. 2022 Nov;36(21):5393-5399.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Obtenir un devis En stock

Other size

Obtenir un devis