RNF24 - ring finger protein 24 Gene

Also Known as G1L

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 11237

About RNF24

Cytogenetic location: 20p13 Genomic coordinates (GRCh38): 20:3,927,311-4,015,558 (from NCBI)

This gene has 4 transcripts (splice variants), 200 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 12.4), brain (RPKM 5.0) and 23 other tissues.

Summary

This gene encodes an integral membrane protein that contains a RING-type zinc finger. The encoded protein may interact with multiple transient receptor potential cation channel subfamily C (TRPC) proteins and regulate the trafficking and insertion of these proteins into the plasma membrane. [provided by RefSeq, Mar 2016]

RNF24 Products (4)

mRNA Protein Name
NM_001134337.3 NP_001127809.1 RING finger protein 24 isoform 1
NM_001134338.3 NP_001127810.1 RING finger protein 24 isoform 2
NM_001321749.2 NP_001308678.1 RING finger protein 24 isoform 1
NM_007219.5 NP_009150.1 RING finger protein 24 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RNF24 Protein Structure

zf-RING_2

zf-RING_2: Ring finger domain (78 - 118)

  • 0
  • 100
  • 148 a.a.
Protein Preferred Names Protein Names

RING finger protein 24

RNF24 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
RNF24 Q9Y225 UQCRH Homo sapiens P07919
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Schopf-Schulz-Passarge Syndrome

  • SSPS

  • Eccrine Tumors With Ectodermal Dysplasia

  • Eccrine Tumors-Ectodermal Dysplasia

  • Keratosis Palmoplantaris-Cystic Eyelids-Hypodontia-Hypotrichosis Syndrome

  • Palmoplantar Hyperkeratosis-Cystic Eyelids-Hypodontia-Hypotrichosis Syndrome

  • Palmoplantar Keratoderma-Cystic Eyelids-Hypodontia-Hypotrichosis Syndrome

  • Keratosis Palmoplantaris With Cystic Eyelids, Hypodontia, And Hypotrichosis

  • Keratosis Palmoplantaris With Cystic Eyelids, Hypodontia And Hypotrichosis
Pasteurellosis

  • Pasteurella Infection

  • Pasteurella Infections

  • Pasteurella Infectious Disease

  • Shipping Fever

  • Transport Fever
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS12083 RNF24 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris RNF24 VGNC VGNC:45664
Mus musculus RNF24 MGD MGI:1261771
Rattus norvegicus RNF24 RGD RGD:1309384
Bos taurus RNF24 VGNC VGNC:34059
Macaca mulatta RNF24 VGNC VGNC:76729
Others RNF24 NCBI