1006-94-6
Chemical Structure
5-Methoxyindole
- CAS No.: 1006-94-6
- Formula:C9H9NO
- Molecular Weight:147.18
IUPAC Name: 5-methoxy-1H-indole
InChIKey: DWAQDRSOVMLGRQ-UHFFFAOYSA-N
SMILES: COC1=CC2=C(NC=C2)C=C1
Biological Activity: 5-Methoxyindole is an L-tryptophan metabolite with antifungal activity, and also serves as a pharmaceutical intermediate. Metabolites of 5-Methoxyindole exhibit COX-2 inhibitory, anti-inflammatory and anti-tumor activities. 5-Methoxyindole induces morphological distortion of hyphae and conidia, ROS accumulation, apoptosis and cell death in Gaeumannomyces graminis. 5-Methoxyindole can be used in studies related to fungal infections and organic synthesis[1][2].
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5-Methoxyindole | 99.20% | 5-Methoxyindole is an L-tryptophan metabolite with antifungal activity, and also serves as a pharmaceutical intermediate. Metabolites of 5-Methoxyindole exhibit COX-2 inhibitory, anti-inflammatory and anti-tumor activities. 5-Methoxyindole induces morphological distortion of hyphae and conidia, ROS accumulation, apoptosis and cell death in Gaeumannomyces graminis. 5-Methoxyindole can be used in studies related to fungal infections and organic synthesis. | ||||||||||||||||||||
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5-Methoxyindole-d3 | 5-Methoxyindole-d3 is the deuterated-labeled 5-Methoxyindole (HY-W007328). 5-Methoxyindole is an L-tryptophan metabolite with antifungal activity, and also serves as a pharmaceutical intermediate. Metabolites of 5-Methoxyindole exhibit COX-2 inhibitory, anti-inflammatory and anti-tumor activities. 5-Methoxyindole induces morphological distortion of hyphae and conidia, ROS accumulation, apoptosis and cell death in Gaeumannomyces graminis. 5-Methoxyindole can be used in studies related to fungal infections and organic synthesis. | |||||||||||||||||||||
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- [1]. Wu KK, et al. 5-methoxyindole metabolites of L-tryptophan: control of COX-2 expression, inflammation and tumorigenesis. Journal of biomedical science. 2014 Mar 03;21(1):17. [Content Brief]
- [2]. Kong M, et al. 5-Methoxyindole, a Chemical Homolog of Melatonin, Adversely Affects the Phytopathogenic Fungus Fusarium graminearum. International Journal of Molecular Sciences, 2021, 22(20): 10991.
Keywords
