100853-61-0
100853-61-0
Chemical Structure
PKI (14-24)amide
- CAS No.: 100853-61-0
- Formula:C49H86N24O15
- Molecular Weight:1251.36
InChIKey: JQHBSZVOKYMQJE-NCSLQZJCSA-N
SMILES: N=C(N)NCCC[C@H](NC(CN)=O)C(N[C@@H]([C@H](O)C)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(N[C@H](C(N)=O)CC(O)=O)=O)CC1=CN=CN1)=O)=O)=O)=O)=O)=O)=O)=O
Biological Activity: PKI (14-24)amide is a potent PKA inhibitor. PKI (14-24)amide strongly inhibited cyclic AMP-dependent protein kinase activity in the cell homogenate[1][2].
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PKI (14-24)amide | PKI (14-24)amide is a potent PKA inhibitor. PKI (14-24)amide strongly inhibited cyclic AMP-dependent protein kinase activity in the cell homogenate. | |||||||||||||||||||||
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References
- [1]. Nörenberg W, et al. Adenosine A2A receptors inhibit the conductance of NMDA receptor channels in rat neostriatal neurons. Amino Acids. 1998;14(1-3):33-9. [Content Brief]
- [2]. Takuma T. Evidence against direct involvement of cyclic AMP-dependent protein phosphorylation in the exocytosis of amylase. Biochem J. 1988 Dec 15;256(3):867-71. [Content Brief]
Keywords
