102042-09-1
Chemical Structure
21-Hydroxyoligomycin A
- CAS No.: 102042-09-1
- Formula:C45H74O12
- Molecular Weight:807.06
IUPAC Name: (1R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18Z,20E,22S,23R,25S,27R,28S,29R)-22-ethyl-7,11,14,15,23-pentahydroxy-6'-((R)-2-hydroxypropyl)-5',6,8,10,12,14,16,28,29-nonamethyl-3',4',5',6'-tetrahydro-2,26-dioxaspiro[bicyclo[23.3.1]nonacosane-27,2'-pyran]
InChIKey: SCVGLVGTMYJVOI-XGJJOKHESA-N
SMILES: C[C@@H]([C@]1([H])OC(/C=C/[C@@H]([C@H]([C@@H](C([C@@H]([C@H]([C@@H]2C)O)C)=O)C)O)C)=O)[C@@](O[C@H]3C[C@H](O)C)(CC[C@@H]3C)O[C@](C[C@H]([C@H](/C=C/C=C\C[C@H]([C@@H]([C@@](O)(C2=O)C)O)C)CC)O)([H])[C@H]1C
Biological Activity: 21-Hydroxyoligomycin A is a potent inhibitor of K-Ras PM localization with an IC50 value of 4.82 nM. 21-Hydroxyoligomycin A has cytotoxicity and can be isolated from Streptomyces[1].
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21-Hydroxyoligomycin A | 21-Hydroxyoligomycin A is a potent inhibitor of K-Ras PM localization with an IC50 value of 4.82 nM. 21-Hydroxyoligomycin A has cytotoxicity and can be isolated from Streptomyces. | |||||||||||||||||||||
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Keywords
