104774-87-0
104774-87-0
Chemical Structure
Cinacalcet metabolite M4
- CAS No.: 104774-87-0
- Formula:C10H12F3N
- Molecular Weight:203.20
IUPAC Name: 3-(3-(trifluoromethyl)phenyl)propan-1-amine
InChIKey: JMTLMFBJIQWJPW-UHFFFAOYSA-N
SMILES: NCCCC1=CC=CC(C(F)(F)F)=C1
Biological Activity: Cinacalcet metabolite M4 is a metabolite of Cinacalcet. Cinacalcet is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease[1][2].
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Cinacalcet metabolite M4 | Cinacalcet metabolite M4 is a metabolite of Cinacalcet. Cinacalcet is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease. | |||||||||||||||||||||
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References
- [1]. Kumar GN, et al. Metabolism and disposition of calcimimetic agent cinacalcet HCl in humans and animalmodels. Drug Metab Dispos. 2004 Dec;32(12):1491-500. [Content Brief]
- [2]. Bushinsky DA, et al. Effect of cinacalcet on urine calcium excretion and supersaturation in genetic hypercalciuric stone-forming rats. Kidney Int. 2006 May;69(9):1586-92. [Content Brief]
