104961-19-5
104961-19-5
Chemical Structure
CI-949
- CAS No.: 104961-19-5
- Formula:C20H20N6O3
- Molecular Weight:392.41
IUPAC Name: 3-isopropoxy-5-methoxy-1-phenyl-N-(1H-tetrazol-5-yl)-1H-indole-2-carboxamide
InChIKey: JPTSIWRGXIZEOO-UHFFFAOYSA-N
SMILES: O=C(C(N1C2=CC=CC=C2)=C(OC(C)C)C3=C1C=CC(OC)=C3)NC4=NN=NN4
Biological Activity: CI-949 is an allergic mediator release inhibitor, which inhibits histamine, leukotriene C4/D4 (LTC4/LTD4), and thromboxane B2 (TXB2) release with IC50s of 11.4 μM, 0.5 μM and 0.1 μM, respectively.
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CI-949 | CI-949 is an allergic mediator release inhibitor, which inhibits histamine, leukotriene C4/D4 (LTC4/LTD4), and thromboxane B2 (TXB2) release with IC50s of 11.4 μM, 0.5 μM and 0.1 μM, respectively. | |||||||||||||||||||||
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Keywords
