105149-00-6
Chemical Structure
Osaterone acetate
- CAS No.: 105149-00-6
- Formula:C22H27ClO5
- Molecular Weight:406.90
IUPAC Name: (4aR,4bS,6aS,7R,9aS,9bR)-7-acetyl-11-chloro-4a,6a-dimethyl-2-oxo-2,4,4a,4b,5,6,6a,7,8,9,9a,9b-dodecahydroindeno[4,5-h]isochromen-7-yl acetate
InChIKey: KKTIOMQDFOYCEN-OFUYBIASSA-N
SMILES: CC(O[C@]1([C@@]2([C@@]([C@@]3([H])[C@]([C@@]4(C(C(Cl)=C3)=CC(OC4)=O)C)([H])CC2)([H])CC1)C)C(C)=O)=O
Biological Activity: Osaterone acetate is an orally active steroid anti-androgen agent, mainly used for benign prostatic hyperplasia (BPH) in dogs. Osaterone acetate competitively antagonizes androgen receptor and inhibits 5α-reductase, reducing the concentration of dihydrotestosterone (DHT) while blocking the growth-stimulating effects of testosterone and DHT on prostate cells. Osaterone acetate can rapidly alleviate the symptoms of BPH in dogs without affecting the fertility of breeding dogs[1].
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Osaterone acetate | Osaterone acetate is an orally active steroid anti-androgen agent, mainly used for benign prostatic hyperplasia (BPH) in dogs. Osaterone acetate competitively antagonizes androgen receptor and inhibits 5α-reductase, reducing the concentration of dihydrotestosterone (DHT) while blocking the growth-stimulating effects of testosterone and DHT on prostate cells. Osaterone acetate can rapidly alleviate the symptoms of BPH in dogs without affecting the fertility of breeding dogs. | |||||||||||||||||||||
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Keywords
