105578-87-8
Chemical Structure
7a-Hydroxyfrullanolide
- CAS. Nr.: 105578-87-8
- Formula:C15H20O3
- Molecular Weight:248.32
IUPAC Name: (3aR,5aR,9bS)-3a-hydroxy-5a,9-dimethyl-3-methylene-3a,4,5,5a,6,7,8,9b-octahydronaphtho[1,2-b]furan-2(3H)-one
InChIKey: XMPDAVDYIOMTLX-NWANDNLSSA-N
SMILES: O[C@]12[C@](OC(C2=C)=O)([H])C3=C(C)CCC[C@@]3(CC1)C
Biological Activity: 7a-Hydroxyfrullanolide has anticancer properties. 7a-Hydroxyfrullanolide reduces polymerization of α-, β-tubulin. 7a-Hydroxyfrullanolide preferrs to bind to β-tubulin over α-tubulin. 7a-Hydroxyfrullanolide also triggers DNA damage response arrests cells in the G2/M-phase. 7a-Hydroxyfrullanolide is an eudesmanolide sesquiterpene lactone (SL) and can be isolated from the flowering plants of the Asteraceae family[1].
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7a-Hydroxyfrullanolide | 7a-Hydroxyfrullanolide has anticancer properties. 7a-Hydroxyfrullanolide reduces polymerization of α-, β-tubulin. 7a-Hydroxyfrullanolide preferrs to bind to β-tubulin over α-tubulin. 7a-Hydroxyfrullanolide also triggers DNA damage response arrests cells in the G2/M-phase. 7a-Hydroxyfrullanolide is an eudesmanolide sesquiterpene lactone (SL) and can be isolated from the flowering plants of the Asteraceae family. | |||||||||||||||||||||
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Keywords
