1065609-00-8

AR453588 Chemical Structure
1065609-00-8

Chemical Structure

AR453588

  • CAS No.: 1065609-00-8
  • Formula:C25H25N7O2S2
  • Molecular Weight:519.64

IUPAC Name: 1-(4-(5-((3-((2-methylpyridin-3-yl)oxy)-5-(pyridin-2-ylthio)pyridin-2-yl)amino)-1,2,4-thiadiazol-3-yl)piperidin-1-yl)ethan-1-one

InChIKey: WITGITFYEMHCEZ-UHFFFAOYSA-N

SMILES: CC(N1CCC(C2=NSC(NC3=NC=C(SC4=NC=CC=C4)C=C3OC5=CC=CN=C5C)=N2)CC1)=O

Biological Activity: AR453588 is a potent and orally bioavailable anti-diabetic glucokinase activator, with an EC50 of 42 nM. AR453588 shows anti-hyperglycemic activity[1].

Cat. No. Product Name Purity Description Pricing
HY-133127
AR453588 99.84% AR453588 is a potent and orally bioavailable anti-diabetic glucokinase activator, with an EC50 of 42 nM. AR453588 shows anti-hyperglycemic activity.
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