109075-64-1
Chemical Structure
WF-10129
- CAS 番号: 109075-64-1
- Formula:C20H28N2O8
- Molecular Weight:424.44
IUPAC Name: (2S,7S)-2-(((S)-1-(((S)-1-carboxy-2-(4-hydroxyphenyl)ethyl)amino)-1-oxopropan-2-yl)amino)-7-hydroxy-4-oxooctanoic acid
InChIKey: VOFCPUVKMIAYMR-SYWGBEHUSA-N
SMILES: OC1=CC=C(C=C1)C[C@@H](C(O)=O)NC([C@H](C)N[C@H](C(O)=O)CC(CC[C@@H](O)C)=O)=O
Biological Activity: WF-10129 is a cytotoxic steroidal compound isolated from the plant Physalis. WF-10129 inhibits liver cancer cell proliferation, induces apoptosis, interferes with metabolism, and significantly reduces lactate production in vitro and in vivo. WF-10129 can also exert anti-tumor activity by regulating the expression of related genes and proteins through the AKT-p53 pathway.
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WF-10129 | WF-10129 is a cytotoxic steroidal compound isolated from the plant Physalis. WF-10129 inhibits liver cancer cell proliferation, induces apoptosis, interferes with metabolism, and significantly reduces lactate production in vitro and in vivo. WF-10129 can also exert anti-tumor activity by regulating the expression of related genes and proteins through the AKT-p53 pathway. | |||||||||||||||||||||
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Keywords
