109304-11-2
109304-11-2
Chemical Structure
2’-Deoxy-2’-fluoro-6-S-Methyl-6-thio-ara-guanosine
- CAS No.: 109304-11-2
- Formula:C11H14FN5O3S
- Molecular Weight:315.32
IUPAC Name: (2R,3R,4S,5R)-5-(2-amino-6-(methylthio)-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
InChIKey: SLPSXWQJKHAIQV-GQTRHBFLSA-N
SMILES: NC1=NC(N([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2F)C=N3)=C3C(SC)=N1
Biological Activity: 2’-Deoxy-2’-fluoro-6-S-Methyl-6-thio-ara-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2’-Deoxy-2’-fluoro-6-S-Methyl-6-thio-ara-guanosine | 2’-Deoxy-2’-fluoro-6-S-Methyl-6-thio-ara-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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