1093278-52-4
1093278-52-4
Chemical Structure
2-Methoxy-2’-deoxy-2’-fluoro-beta-D-arabinoadenosine
- CAS No.: 1093278-52-4
- Formula:C11H14FN5O4
- Molecular Weight:299.26
IUPAC Name: (2R,3R,4S,5R)-5-(6-amino-2-methoxy-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
InChIKey: NRLVIGDRRHAGSY-GQTRHBFLSA-N
SMILES: O[C@H]1[C@H](F)[C@H](N(C=N2)C3=C2C(N)=NC(OC)=N3)O[C@@H]1CO
Biological Activity: 2-Methoxy-2’-deoxy-2’-fluoro-beta-D-arabinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2-Methoxy-2’-deoxy-2’-fluoro-beta-D-arabinoadenosine | 2-Methoxy-2’-deoxy-2’-fluoro-beta-D-arabinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
