113-92-8
113-92-8
Chemical Structure
Chlorpheniramine maleate
Synonym(s): Chlorphenamine maleate
- CAS No.: 113-92-8
- Formula:C20H23ClN2O4
- Molecular Weight:390.86
IUPAC Name: 3-(4-chlorophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine maleate
InChIKey: DBAKFASWICGISY-BTJKTKAUSA-N
SMILES: CN(C)CCC(C1=CC=C(Cl)C=C1)C2=CC=CC=N2.O=C(O)/C=C\C(O)=O
Biological Activity: Chlorpheniramine maleate is a histamine H1 receptor antagonist with an IC50 of 12 nM[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Chlorpheniramine maleate | 99.67% | Chlorpheniramine maleate is a histamine H1 receptor antagonist with an IC50 of 12 nM. | ||||||||||||||||||||
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Chlorpheniramine maleate (Standard) | 99.37% | Chlorpheniramine (maleate) (Standard) is the analytical standard of Chlorpheniramine (maleate). This product is intended for research and analytical applications. Chlorpheniramine maleate is a histamine H1 receptor antagonist with an IC50 of 12 nM. | ||||||||||||||||||||
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Chlorpheniramine-d4 maleate | Chlorpheniramine-d4 (maleate) is deuterium labeled Chlorpheniramine (maleate). | |||||||||||||||||||||
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Chlorpheniramine-d6 maleate | Chlorpheniramine-d6 (maleate) is the deuterium labeled Chlorpheniramine maleate. | |||||||||||||||||||||
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References
- [1]. Medina, M.A., et al., Chlorpheniramine inhibits the synthesis of ornithine decarboxylase and the proliferation of human breast cancer cell lines. Breast Cancer Res Treat, 1995. 35(2): p. 187-94. [Content Brief]
- [2]. Kelly, J.X., et al., Design, synthesis, and evaluation of 10-N-substituted acridones as novel chemosensitizers in Plasmodium falciparum. Antimicrob Agents Chemother, 2007. 51(11): p. 4133-40. [Content Brief]
- [3]. Iemura, R., et al., Synthesis of 2-(4-substituted-1-piperazinyl)benzimidazoles as H1-antihistaminic agents. J Med Chem, 1986. 29(7): p. 1178-83. [Content Brief]
